genome-wideassociationstudies相关论文
Anorexia nervosa(AN)is a complex disorder with a strong genetic component.Comorbidities are frequent and there is substa......
INTRODUCTION Genome-wide association studies (GWAS) typically using single nucleotide polymorphism (SNP) as the basic un......
Genetic variants in ERAP1 and NCF2 in the MHC class I related genes are associated with non-small ce
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With the rapidly development of DNA sequencing and bioinformatics technique,a huge amount of high-dimensional single-nuc......
Combining high-throughput phenotyping and GWAS to accelerate the dissection of rice genetic architec
As plant genomics rapidly develops with the use of high-throughput sequencing techniques,plant phenotyping lags far behi......
Objective Genome-wide association studies(GWASs)have identified hundreds of cancer-associated single nucleotide polymorp......
We present a new statistical test of association between a trait and genetic markers,which we theoretically and practica......
A global alfalfa diversity panel reveals genomic selection signatures in Chinese varieties and genom
Alfalfa (Medicago sativa L.) is an important forage crop worldwide. However, little is known about the effects of breedi......
Epidemiological studies have linked adult height with breast cancer risk in women.However,the magnitude of the assoc......
High power, low false positive rate and fast methodologies for genome-wide association studies and l
Genome-wide association studies (GWAS) have been widely used in genetic dissection of complex traits.However,common meth......
Genome-wide association studies with drought related metabolic changes in maize to improve drought t
Drought is a severe limiting factor for maize production in developing countries.Plants response to water stress depends......
强直性脊柱炎( AS)是一种涉及多种危险因素的复杂性疾病,主要为遗传和环境两方面因素,其中人类白细胞抗原( HLA)-B27是 AS的主要易患基因......
天疱疮是一组少见、严重时可危及生命的自身免疫性大疱性疾病,好发于40~60岁中年人,寻常型天疱疮(PV)是天疱疮最常见的一型。它是一种典......
痛风是一种常见的由尿酸盐沉积引起的慢性炎症性关节炎。该文总结了最新的痛风遗传学基础,发现痛风的高风险基因多数与肾脏和肠道尿......
Background:Genome-wide association studies(GWASs)have identified thousands of genetic variants that are associated with ......